Bryant eclipses 30,000, Lakers beat Hornets 103-87


NEW ORLEANS (AP) — Kobe Bryant grinned and uttered the word "irony" as he considered the fact that the team that drafted him nearly 17 years ago was his opponent on the night he eclipsed a scoring milestone to join an exclusive club of NBA greats.


It's easy to forget that it was the Hornets who drafted and then traded Bryant away back in 1996.


In the years since, the Hornets have changed cities, from Charlotte to New Orleans, and Bryant has become one of five players in NBA history to score 30,000 points, surpassing the mark with a 29-point performance that helped the Lakers to a 103-87 triumph Wednesday night.


"It's funny how sports always seems to kind of have that connectivity, in some shape, form or fashion," Bryant said. "It just always seems to come full circle."


Bryant entered the game needing 13 points to make history and no one doubted he would get it. NBA Commissioner David Stern, who happened to be making a scheduled visit with new Hornets owner Tom Benson, offered Bryant a congratulatory hand shake before tip-off.


Bryant had 17 points by halftime, eclipsing the 30,000-mark with a short jumper in the paint over Robin Lopez late in the first half. That might have been the least spectacular of his baskets, which included the usual array of soaring dunks, demoralizing transition 3-pointers and twisting, off-balance jumpers.


The only other players to score more than 30,000 are Kareem Abdul-Jabbar, Karl Malone, Michael Jordan and Wilt Chamberlain.


"It's pretty awesome," Bryant said. "These are players I respect tremendously and obviously grew up idolizing and watching and learned a great deal from."


When Lakers coach Mike D'Antoni was asked before tipoff about Bryant's impending milestone, the coach joked, "That just means he is old."


In fact, at 34, Bryant is younger than the other four were when they hit the mark, but Bryant also turned pro at 18, and is in his 17th season.


"Honestly, I don't know why I'm still working as hard as I am after 17 years," Bryant said. "That's the thing that I'm most proud of — every year, every day working hard at it. It's a lot of years, a lot of work."


Dwight Howard added 18 points and five blocked shots for the Lakers, who trailed 48-47 at halftime, but seized control with a 13-0 run to open the third quarter, and the lead grew as large as 20 in the fourth.


Ryan Anderson scored 31 points, hitting 5 of 8 3-pointers for the Hornets, who were playing their ninth straight game without top overall draft choice Anthony Davis. Greivis Vasquez added 16 points, while Lopez scored 15 points and blocked five shots.


Antawn Jamison scored 15 and Metta World Peace 11, and Chris Duhon had 10 assists for Los Angeles, which is playing without Steve Nash and Pau Gasol and won for only the second time on the road this season. The Hornets fell to 3-7 at home and lost for the 10th time in 12 games overall.


The Hornets led from early in the first quarter until halftime, going up by as many as eight points when Al-Farouq Aminu slammed down an alley-oop lob from Vasquez, energizing the largest crowd of the season at the New Orleans Arena.


Bryant helped the Lakers trim their deficit after that, hitting five free throws and his milestone on 3-foot jumper in the last 2:15 of the second quarter.


Jamison opened the third-quarter onslaught with 3, Howard followed with a fast-break layup and Bryant had two straight fast-break dunks, one of which he created with a steal. Howard finished the surge with a layup.


"I just didn't think our defense was there, especially that first five or six minutes of the third quarter," Hornets coach Monty Williams said. "Our defense was really poor, and we can't afford those lapses."


After the game, Bryant sat in his locker, reflecting on the elite company he now keeps in NBA history, and the things he sees in younger, prolific scoring stars like Oklahoma City's Kevin Durant, whom the Lakers will face on Friday night, and who could very well join the 30,000-point club at the rate he's going.


One common characteristic, Bryant said, is an apparent immunity to both pressure and criticism.


"Scorers kind of have a fighter-pilot mentality. We're a different breed," he said. "But there are different positions. We scored in a myriad of ways. We all went about it differently in different situations. It's fun to see."


NOTES: Before attending the game, Stern toured the headquarters of the New Orleans Saints, also owned by Benson, and saw how Benson's plans for the NBA franchise were taking shape. New construction has begun on additions that will also accommodate Hornets offices and practice courts. .... Stern said he was pleased to be able to also see Bryant surpass the 30,000-point mark in person. "As a talent, a competitor, I think that he is up there on the pedestal with Michael Jordan," Stern said. "He is one of the greatest." ... Stern also discussed the possibility of a team name change for New Orleans, something Benson has said he wants since buying the club last spring. Stern says the club has not yet applied for a name change but that the league would likely accept whatever name the Hornets want and expedite the transition.


Read More..

Celebrations planned as Wash. legalizes marijuana


SEATTLE (AP) — Legal marijuana possession becomes a reality under Washington state law on Thursday, and some people planned to celebrate the new law by breaking it.


Voters in Washington and Colorado last month made those the first states to decriminalize and regulate the recreational use of marijuana. Washington's law takes effect Thursday and allows adults to have up to an ounce of pot — but it bans public use of marijuana, which is punishable by a fine, just like drinking in public.


Nevertheless, some people planned to gather at 12:01 a.m. PST Thursday to smoke in public beneath Seattle's Space Needle. Others planned a midnight party outside the Seattle headquarters of Hempfest, the 21-year-old festival that attracts tens of thousands of pot fans every summer.


"This is a big day because all our lives we've been living under the iron curtain of prohibition," said Hempfest director Vivian McPeak. "The whole world sees that prohibition just took a body blow."


In another sweeping change for Washington, Gov. Chris Gregoire on Wednesday signed into law a measure that legalizes same-sex marriage. The state joins several others that allow gay and lesbian couples to wed.


That law also takes effect Thursday, when gay and lesbian couples can start picking up their wedding certificates and licenses at county auditors' offices. Those offices in King County, the state's largest and home to Seattle, and Thurston County, home to the state capital of Olympia, planned to open the earliest, at 12:01 a.m. Thursday, to start issuing marriage licenses. Because the state has a three-day waiting period, the earliest that weddings can take place is Sunday.


The Seattle Police Department provided this public marijuana use enforcement guidance to its officers via email Wednesday night: "Until further notice, officers shall not take any enforcement action — other than to issue a verbal warning — for a violation of Initiative 502."


Thanks to a 2003 law, marijuana enforcement remains the department's lowest priority. Even before I-502 passed on Nov. 6, police rarely busted people at Hempfest, despite widespread pot use, and the city attorney here doesn't prosecute people for having small amounts of marijuana.


Officers will be advising people to take their weed inside, police spokesman Jonah Spangenthal-Lee wrote on the SPD Blotter. "The police department believes that, under state law, you may responsibly get baked, order some pizzas and enjoy a 'Lord of the Rings' marathon in the privacy of your own home, if you want to."


Washington's new law decriminalizes possession of up to an ounce for those over 21, but for now selling marijuana remains illegal. I-502 gives the state a year to come up with a system of state-licensed growers, processors and retail stores, with the marijuana taxed 25 percent at each stage. Analysts have estimated that a legal pot market could bring Washington hundreds of millions of dollars a year in new tax revenue for schools, health care and basic government functions.


But marijuana remains illegal under federal law. That means federal agents can still arrest people for it, and it's banned from federal properties, including military bases and national parks.


The Justice Department has not said whether it will sue to try to block the regulatory schemes in Washington and Colorado from taking effect.


"The department's responsibility to enforce the Controlled Substances Act remains unchanged," said a statement issued Wednesday by the Seattle U.S. attorney's office. "Neither states nor the executive branch can nullify a statute passed by Congress" — a non-issue, since the measures passed in Washington and Colorado don't "nullify" federal law, which federal agents remain free to enforce.


The legal question is whether the establishment of a regulated marijuana market would "frustrate the purpose" of the federal pot prohibition, and many constitutional law scholars say it very likely would.


That leaves the political question of whether the administration wants to try to block the regulatory system, even though it would remain legal to possess up to an ounce of marijuana.


Colorado's measure, as far as decriminalizing possession goes, is set to take effect by Jan. 5. That state's regulatory scheme is due to be up and running by October 2013.


___(equals)


Johnson can be reached at https://twitter.com/GeneAPseattle


Read More..

Individuality takes center stage at Grammys


Fun. helped break up the sound of dance and electronic music on Top 40 radio with its edgy pop-rock grooves. Frank Ocean made a bold statement in R&B — with an announcement about his sexuality and with his critically revered, multi-genre album, "channel ORANGE." And Mumford & Sons continued to bring its folk-rock swag and style to the Billboard charts with its sophomore album.


They all were rewarded Wednesday when The Recording Academy announced the nominees for the 2013 Grammy Awards.


Those acts, who scored the most nominations with six each, were joined by typical Grammy contenders like Jay-Z and Kanye West, who also got six nominations. The Black Keys' drummer, Dan Auerbach, is also up for six awards, thanks to his nomination for producer of the year. His band earned five nods, along with R&B singer Miguel and jazz pianist Chick Corea.


"It feels like alternative music is back," said fun. guitarist Jack Antonoff. His band's gold-selling "Some Nights" is up for album of the year, competing with Black Keys' "El Camino," Mumford & Sons' "Babel," Jack White's "Blunderbuss" and "channel ORANGE," the major label debut from Ocean.


Fun. is nominated in all of the major categories, including best new artist, and record and song of the year for its breakthrough anthem "We Are Young."


Ocean, whose mother attended the nominations special, scored nods in three of the top four categories. His song "Thinkin Bout You" — which he originally wrote for another singer — will compete for record of the year with Black Keys' "Lonely Boy" and four No. 1 hits: Taylor Swift's "We Are Never Ever Getting Back Together," ''Somebody I Used to Know" by Gotye and Kimbra, Kelly Clarkson's "Stronger (What Doesn't Kill You)" and "We Are Young" by fun.


Song of the year, too, features some No. 1 hits, including fun. and Clarkson's jams, as well as Carly Rae Jepsen's viral smash "Call Me Maybe." But then there's Ed Sheeran's "The A Team," a slow groove about a homeless prostitute, and Miguel's "Adorn," the R&B singer-songwriter's crossover hit.


"It's like one of those songs that wrote itself and I was the vessel," the 26-year-old said in an phone interview from New York City late Wednesday, where he performed with Trey Songz and Elle Varner.


While Miguel's excited to compete for song of the year, he's more thrilled about his sophomore album's nomination for best urban contemporary album, a new category that recognizes R&B albums with edge and multiple sounds.


"That's a huge complement to say that your entire body of work was the best of the year," he said of "Kaleidoscope Dream." ''That's the one that means the most to me. I'm really hoping maybe, just maybe."


Miguel, along with Gotye, Alabama Shakes and the Lumineers, is part of the pack of nominees who have showcased individuality and have marched to the beat of their own drum in today's music industry.


Though nominated albums by The Black Keys and Mumford & Sons are platinum-sellers, their songs are not regularly heard on Top 40 radio. Electronic and dance music, which has dominated radio airplay for a few years, were left out of the top awards this year. Also, One Direction — the boy band that released two top-selling albums this years and sold-out many arenas — was snubbed for best new artist.


Lionel Richie has one of the year's top-selling albums with his country collaboration collection, "Tuskegee," but he didn't earn any nominations. And Nicki Minaj, who released a gold-selling album this year and had a hit with "Starships," wasn't nominated for a single award.


Jay-Z and West dominated the rap categories, a familiar refrain at the Grammys. Nas scored four nominations, including best rap album for "Life Is Good." Jeff Bhasker, the producer behind fun.'s breakthrough album, also scored four nods.


Swift, who released her latest album, "Red," after the Grammy eligibility date, still scored three nominations, including two for "Safe & Sound" with The Civil Wars. Country acts were mainly left out of the major categories this year, though the genre usually has success at the Grammys. Aside from Swift's pop song competing for record of the year, there is 21-year-old Hunter Hayes, who is up for best new artist against fun., Ocean, Alabama Shakes and the Lumineers.


"I'm so proud to be, as you say, representing country music in the new artist category," said Hayes, who is also nominated for best country album and country solo performance. "I don't even feel worthy of saying that, but it's so cool for me to be able to say that."


Swift hosted the CBS special with LL Cool J and it featured performances by The Who and Maroon 5, who received multiple nominations.


The five-year-old nominations show spent its first year outside Los Angeles, making its debut in Nashville, Tenn., at the Bridgestone Arena. It marked the largest venue the show has been held in.


The 55th annual Grammy Awards take place Feb. 10 in Los Angeles.


___


Online:


http://www.grammys.com


___


AP Music Writer Chris Talbott and AP Writer Caitlin R. King in Nashville contributed to this report.


Read More..

Local sales of homes in foreclosure jump 65% in 3Q









Sales of Chicago-area homes in the foreclosure process but not yet repossessed by banks soared during the third quarter, RealtyTrac reported Thursday.

The online foreclosure marketplace said 3,531 pre-foreclosure homes in the greater Chicago area sold in the three months that ended in September, up 34 percent from the second quarter and 65 percent year-over-year. Separately, third-quarter sales of repossessed, bank-owned properties rose to 5,731 properties, up 37 percent from June and 45 percent from 2011's third quarter.

Increased sales of distressed homes are a good sign for the market's long-term health because overall prices will rise as discounted properties are removed from the market. Also, the increase in pre-foreclosure short sales has enabled homeowners to benefit from the Mortgage Forgiveness Debt Relief Act, which does not treat the forgiven part of the unpaid debt as taxable income. The legislation is set to expire at year's end.

Natiionally, the 98,125 pre-foreclosure short sales completed during the third quarter just outnumbered the sale of 94,934 bank-owned properties.

"The shift toward earlier disposition of distressed properties continued in the third quarter as both lenders and at-risk homeowners are realizing that short sales are often a better alternative than foreclosure," said Daren Blomquist, a RealtyTrac vice president.

However, he added, "The prospect of being taxed on potentially tens or hundreds of thousands of dollars in additional income may motivate more distressed homeowners to forgo a short sale and allow the home to be foreclosed."

On average, Chicago-area homes sold through short sales, a transaction where the homeowner sells the property for less than the amount owed on the mortgage, with the bank's permission, sold for an average discount of 41 percent from non-distressed sales. Bank-owned homes sold at an average discount of 54 percent.

RealtyTrac said sales of distressed properties accounted for 28 percent of Chicago-area home sales during the third quarter. The company's definition of the Chicago area extends from southern Wisconsin to Northwest Indiana.

mepodmolik@tribune.com | Twitter @mepodmolik



Read More..

Jazz legend Dave Brubeck dead








Dave Brubeck, a jazz musician who attained pop-star acclaim with recordings such as "Take Five" and "Blue Rondo a la Turk," died Wednesday morning at Norwalk Hospital, in Norwalk, Conn., said his longtime manager-producer-conductor Russell Gloyd.


Brubeck was one day short of his 92nd birthday. He died of heart failure, en route to "a regular treatment with his cardiologist,” said Gloyd.


Throughout his career, Brubeck defied conventions long imposed on jazz musicians. The tricky meters he played in “Take Five” and other works transcended standard conceptions of swing rhythm.






The extended choral/symphonic works he penned and performed around the world took him well outside the accepted boundaries of jazz. And the concerts he brought to colleges across the country in the 1950s shattered the then-long-held notion that jazz had no place in academia.


As a pianist, he applied the classical influences of his teacher, the French master Darius Milhaud, to jazz, playing with an elegance of tone and phrase that supposedly were the antithesis of the American sound.


As a humanist, he was at the forefront of integration, playing black jazz clubs throughout the deep South in the ’50s, a point of pride for him.


"For as long as I’ve been playing jazz, people have been trying to pigeonhole me,” he once told the Tribune.


"Frankly, labels bore me."


He is survived by his wife, Iola; four sons and a daughter; grandsons and a great granddaughter.






Read More..

Apple shares tumble 4 percent in heavy trade


NEW YORK/SAN FRANCISCO (Reuters) - Shares of Apple Inc tumbled nearly 4 percent on Wednesday, rounding off a bleak ten weeks for the most valuable U.S. company, with analysts citing factors such as increasing competition in the tablet market.


The stock was one of the biggest percentage losers on the S&P 500, dropping 5.2 percent to $545.56 at one point as more than 17 million shares changed hands, putting it on track to surpass the company's average daily volume over 50 days of 21 million shares.


The stock's massive size meant the retreat was responsible for two-thirds of the 1.1 percent decline in the Nasdaq 100 Index on Wednesday.


Analysts gave different reasons for the decline. Some cited a research report saying the company will lose share in the tablet computer space next year. Others cited reports of higher margin requirements at clearing firms, and several investors said uncertain tax rates on capital gains in 2013 prompted selling.


"Depending on what happens with the (U.S. fiscal negotiations), rates could rise next year or they could stay the same," Brian Battle, director of trading at Performance Trust Capital Partners in Chicago, said. "They will not be lower, so if you're an investor who has seen gains in Apple, it is better to take those gains this year rather than next."


Apple is still up 36 percent so far this year, but has been weak recently, dropping into bear market territory. The stock is now down nearly 22 percent from its all-time high of $705.07 a share of September 21.


Some were perplexed at the sudden falling out of favor of the stock, which so far has been a staple in almost all growth portfolios.


"Apple stock is significantly more volatile than its earnings and innovation stream," Daniel Ernst, analyst with Hudson Square Research said. "And yet the wind blows slightly from the south instead of the east one particular morning and the stock is down 6 percent."


"It makes no sense. There are lines around the block for their products all around the world," he added. "No other company has that."


On Wednesday, research firm International Data Corp said Apple would shed market share in the tablet computer space for all of 2012, with consumers favoring devices that run on Google's Android platform instead of Apple's popular iPad product line.


Apple's worldwide tablet market share would slip to 53.8 percent in 2012 from 56.3 percent in 2011, while Android products would increase their share to 42.7 percent from 39.8 percent, IDC said.


The main reason for the negative sentiment around the stock is likely concerns about new competition in the tablet market, Colin Gillis, an analyst with BGC Partners, adding that some investors who were hoping for a special dividend this year may be disappointed as time is running out.


"If you were expecting special dividend by year end, that's less likely to happen because its December 5," he said.


TAX SELLING


Separately, Nokia is to partner with China Mobile, the world's biggest mobile operator, in a sales deal that will give the Finnish company an opportunity to win back Chinese market share from Apple's iPhone.


"This is not going to be a short-term trend. This is a management test, of how well they can perform without (deceased former chief executive) Steve Jobs," said Battle.


Referring to one of Apple's most recent product launches, a version of the iPad that was smaller but not a new product category, Battle said Apple would need "another home run" for shares to return to levels around $700.


"They need another new product that hits it out of the park. Without that, they could get a gradual grind-down in confidence," he said.


The 7.9-inch iPad mini marks Apple's first foray into the smaller-tablet segment and is the company's first major new device since the death of co-founder Jobs last year.


While lines for the new iPads had appeared lighter than usual when it hit stores in November, the company said at that time that demand was so strong that it "practically sold out of iPad minis". It said it sold 3 million of its new iPads -- including the newer full-size version -- in the first three days on the market.


Apple is currently ramping up the introduction of its latest iPhone 5 smartphone and smaller iPad mini tablet in international markets. The company is launching the iPhone 5 in 50 countries in December, including China and South Korea.


Some analysts suggested that investors also sold shares of Apple amid uncertainty over ongoing fiscal negotiations in Washington. If no agreement is reached on the issue, higher taxes on dividends and capital gains are possible in 2013. That has prompted some investors to lock in profits now, particularly on a stock like Apple, which has posted gains of at least 25 percent for four consecutive years.


Tax selling "can take a life of its own," said Tim Ghriskey, chief investment officer of Solaris Group in Bedford Hills, New York.


"Some taxable investors take the gains, that creates some negative momentum, institutional investors are heavily weighted the stock and reduce exposure."


(Additional reporting by Charles Mikolajczak in New York and Doris Frankel in Chicago; Editing by Bernadette Baum and Andrew Hay)



Read More..

IOC strips 4 medals from 2004 Athens Olympics


LAUSANNE, Switzerland (AP) — The IOC has stripped medals from four athletes caught doping at the 2004 Athens Olympics — including one gold medalist — and postponed a decision to revoke Lance Armstrong's bronze from the 2000 Sydney Games.


The IOC on Wednesday disqualified four athletes whose Athens doping samples were retested earlier this year and came back positive, including shot put gold medalist Yuriy Bilonog of Ukraine.


The others are hammer throw silver medalist Ivan Tskikhan of Belarus and two bronze medalists — women's shot putter Svetlana Krivelyova of Russia and discus thrower Irina Yatchenko of Belarus.


The case of a fifth bronze medalist, weightlifter Oleg Perepechenov of Russia, remains pending.


Read More..

“The Message” deemed greatest hip hop song ever












LOS ANGELES (Reuters) – The 1982 hit “The Message” by Grandmaster Flash and the Furious Five was named the greatest hip hop song of all time on Wednesday, in the first such list by Rolling Stone magazine to celebrate the young but influential music genre.


“The Message,” which tops a list of 50 influential hip hop songs, was the first track “to tell, with hip hop‘s rhythmic and vocal force, the truth about modern inner-city life in America,” Rolling Stone said.












Grandmaster Flash and the Furious Five, a hip hop collective from the south Bronx in New York, was formed in 1978 and became one of the pioneers of the hip hop genre.


The full list spanned songs ranging from Sugarhill Gang’s 1979 hit “Rapper’s Delight,” which came in at No. 2, to Kanye West‘s 2004 hit “Jesus Walks,” which landed at No. 32.


“It’s a list that would have been a lot harder to do ten or 15 years ago because hip hop is so young,” Nathan Brackett, deputy managing editor of Rolling Stone, told Reuters.


“We’ve reached the point now where hip hop acts are getting into the (Rock and Roll) Hall Of Fame… it just felt like the right time to give this the real Rolling Stone treatment.”


Rolling Stone‘s top 10 featured mostly hip hop veterans, such as Run-D.M.C.’s 1983 track “Sucker M.C.’s,” Dr. Dre and Snoop Dogg’s 1992 hit “Nuthin’ But A ‘G’ Thang,” Public Enemy’s 1990 song “Fight The Power” and Notorious B.I.G’s 1994 hit “Juicy.”


Other influential artists in the top 50 songs included Beastie Boys, who came in at No. 19 with “Paul Revere,” and recordings by Jay-Z, Eminem, Missy Elliot, Outkast, Lauryn Hill, LL Cool J, Nas and the late rapper 2Pac.


The list of 50 songs was compiled by a 33-panel of members comprising Rolling Stone editors and hip hop experts. They included musician Ahmir “Questlove” Thompson of The Roots, who Brackett described as “an incredible encyclopedia” of both old and new hip hop knowledge.


Brackett noted that some songs considered to be one-hit wonders, such as Audio Two’s 1988 hit “Top Billin’,” made the final selection.


“The references in those songs become the building blocks of all these other songs down the road … they become touchstones, really part of the meat of hip hop songs going forward,” Brackett said.


The full list will be released online at RollingStone.com and in the pop culture magazine on newsstands on December7. The issue will feature four different covers of Eminem, Jay-Z, Notorious B.I.G. and 2Pac.


(Reporting By Piya Sinha-Roy, editing by Jill Serjeant)


Music News Headlines – Yahoo! News


Read More..

Longer tamoxifen use cuts breast cancer deaths


Breast cancer patients taking the drug tamoxifen can cut their chances of having the disease come back or kill them if they stay on the pills for 10 years instead of five years as doctors recommend now, a major study finds.


The results could change treatment, especially for younger women. The findings are a surprise because earlier research suggested that taking the hormone-blocking drug for longer than five years didn't help and might even be harmful.


In the new study, researchers found that women who took tamoxifen for 10 years lowered their risk of a recurrence by 25 percent and of dying of breast cancer by 29 percent compared to those who took the pills for just five years.


In absolute terms, continuing on tamoxifen kept three additional women out of every 100 from dying of breast cancer within five to 14 years from when their disease was diagnosed. When added to the benefit from the first five years of use, a decade of tamoxifen can cut breast cancer mortality in half during the second decade after diagnosis, researchers estimate.


Some women balk at taking a preventive drug for so long, but for those at high risk of a recurrence, "this will be a convincer that they should continue," said Dr. Peter Ravdin, director of the breast cancer program at the UT Health Science Center in San Antonio.


He reviewed results of the study, which was being presented Wednesday at a breast cancer conference in San Antonio and published by the British medical journal Lancet.


About 50,000 of the roughly 230,000 new cases of breast cancer in the United States each year occur in women before menopause. Most breast cancers are fueled by estrogen, and hormone blockers are known to cut the risk of recurrence in such cases.


Tamoxifen long was the top choice, but newer drugs called aromatase inhibitors — sold as Arimidex, Femara, Aromasin and in generic form — do the job with less risk of causing uterine cancer and other problems.


But the newer drugs don't work well before menopause. Even some women past menopause choose tamoxifen over the newer drugs, which cost more and have different side effects such as joint pain, bone loss and sexual problems.


The new study aimed to see whether over a very long time, longer treatment with tamoxifen could help.


Dr. Christina Davies of the University of Oxford in England and other researchers assigned 6,846 women who already had taken tamoxifen for five years to either stay on it or take dummy pills for another five years.


Researchers saw little difference in the groups five to nine years after diagnosis. But beyond that time, 15 percent of women who had stopped taking tamoxifen after five years had died of breast cancer versus 12 percent of those who took it for 10 years. Cancer had returned in 25 percent of women on the shorter treatment versus 21 percent of those treated longer.


Tamoxifen had some troubling side effects: Longer use nearly doubled the risk of endometrial cancer. But it rarely proved fatal, and there was no increased risk among premenopausal women in the study — the very group tamoxifen helps most.


"Overall the benefits of extended tamoxifen seemed to outweigh the risks substantially," Dr. Trevor Powles of the Cancer Centre London wrote in an editorial published with the study.


The study was sponsored by cancer research organizations in Britain and Europe, the United States Army, and AstraZeneca PLC, which makes Nolvadex, a brand of tamoxifen, which also is sold as a generic for 10 to 50 cents a day. Brand-name versions of the newer hormone blockers, aromatase inhibitors, are $300 or more per month, but generics are available for much less.


The results pose a quandary for breast cancer patients past menopause and those who become menopausal because of their treatment — the vast majority of cases. Previous studies found that starting on one of the newer hormone blockers led to fewer relapses than initial treatment with tamoxifen did.


Another study found that switching to one of the new drugs after five years of tamoxifen cut the risk of breast cancer recurrence nearly in half — more than what was seen in the new study of 10 years of tamoxifen.


"For postmenopausal women, the data still remain much stronger at this point for a switch to an aromatase inhibitor," said that study's leader, Dr. Paul Goss of Massachusetts General Hospital. He has been a paid speaker for a company that makes one of those drugs.


Women in his study have not been followed long enough to see whether switching cuts deaths from breast cancer, as 10 years of tamoxifen did. Results are expected in about a year.


The cancer conference is sponsored by the American Association for Cancer Research, Baylor College of Medicine and the UT Health Science Center.


___


Marilynn Marchione can be followed at http://twitter.com/MMarchioneAP


Read More..

Possible Wintour appointment gets London talking


LONDON (AP) — Thomas Jefferson, Ben Franklin, John Quincy Adams ... and now Anna Wintour?


A report suggesting that the influential editor-in-chief of Vogue is one of the candidates being considered for the top U.S. diplomatic post in France or Britain has sparked spirited debate about her qualifications, exciting Britain's glamour-hungry tabloids but raising hackles at the conservative Daily Telegraph.


"Anna Wintour may be an enticing pick for a celebrity-fixated White House," wrote Nile Gardner in the Telegraph. "But she is eminently unsuitable for America's most prestigious diplomatic posting."


The possibility that the British-born Wintour would move into London's grand ambassadorial residence was raised several years ago by The Guardian newspaper — where her brother Patrick is a prominent journalist — and again this week by Bloomberg News, which based its report on "two people familiar with the matter."


Officials at the U.S. Embassy in London said they would not speculate on President Obama's eventual choice for a successor to Ambassador Louis Susman, who has announced plans to step down. White House officials have also refused to comment.


Officials caution that a decision is months away and would only follow the appointment of a new secretary of state to replace outgoing Hillary Clinton and would also include a thorough vetting process.


Guardian fashion writer Jess Cartner-Morley said the editor — the model for the imperious character played by Meryl Streep in "The Devil Wears Prada" movie — would be well-suited for an ambassadorial position.


"Wintour is generally acknowledged as whipsmart and extremely hard-working," she wrote. "She is enormously charismatic, a born networker and a formidable fundraiser."


Cartner-Morley also challenged the dismissive view that Wintour's many years in the fashion industry are not enough, citing recent ambassadorial choices of a retired investment banker and a retired car dealership owner.


"Is a career as one of the biggest global players in an industry estimated to be worth $900 billion to the world economy really so inferior and shallow by comparison?" the writer asked.


Vogue spokeswoman Megan Salt in New York said Wednesday said that Wintour is very happy with her present job.


Wintour raised $40 million for Obama's re-election through a number of campaigns and star-studded dinners she co-hosted with some of the most powerful people in the entertainment and fashion worlds. In August, she teamed up with movie mogul Harvey Weinstein for a fundraising dinner, after a successful party at Sarah Jessica Parker's Manhattan home in July.


The ambassadorial posts in France and Britain — formally known as the Court of St. James's — are among the most coveted in the diplomatic ranks. They also typically go to wealthy individuals willing to use personal funds to buttress the government-provided entertainment budget.


Wintour, 63, is best-known for her trademark glossy bob hairstyle, oversized sunglasses and haughty demeanor. Born in London, she started in fashion journalism at Harper's Bazaar and New York magazine, and after working at the helm of other glossies became editor-in-chief at U.S. Vogue in 1988.


Carne Ross, a former British diplomat who now runs a New York-based diplomatic advisory group, said Wintour's skills — "honed in the vicious world of the fashion industry" — would qualify her for a diplomatic posting.


Ross said a large part of an ambassador's job involves taking part in social gatherings, something Wintour would be comfortable with. Often most of the real political work is done by direct communications between the White House and the prime minister's office at Downing Street, he said.


"That diminishes the political significance of the ambassador's role," he said.


Mary Jo Jacobi, a presidential adviser during two Republican administrations, said Wintour would be an unusual choice but possibly an effective one.


"Vogue is a very successful, very large publication, and she has experience with big budgets and with challenging, difficult people," Jacobi said. "She knows how to marshal resources. And her job has involved a great deal of diplomacy."


Read More..